Menthyl Nicotinate
Nicomenthyl® is a multifunctional sensorial cosmetic active, derived from Vitamin B3 (Niacin or Nicotinic acid), composed of pure Menthyl nicotinate.
Fast percutaneous delivery
Rapidly absorbed through the skin barrier and slowly hydrolyzed by esterase.
Skin micro-circulation enhancement
Significantly activates skin microcirculation without causing any unpleasant effect.
Detox & Repair Efficacy
Protective and detoxifying activity against oxidant agents & UV radiations, cigarette smoke & urban dust, blue light & Wi-Fi.
No bothersome "flush"
Simultaneous and time-release delivery of niacin and menthol prevents excessive and bothersome flush.
Carrier effect
Acts as a fixative, carrier and booster for other beneficial lipophilic actives.
NAD-Boosting effect
Very powerful NAD-boosting molecule, and thus instrumental to protect and repair the skin barrier.
Self-emulsifying properties
Being an amphiphilic molecule, supported by appropriate thickening agents, has self-emulsifying properties.
NICOMENTHYL RANGE
Nicomenthyl 20 is
pure
Menthyl nicotinate
(purity grade > 98.0%).
Nicomenthyl TAO combines the properties of Menthyl Nicotinate with
anti inflammatory and immunostimulant effects of Curcumin.
Nicomenthyl Hot combines the properties of Menthyl Nicotinate with the tonic and warming cosmetic effect of Vanillyl Butyl Ether.
Nicomenthyl Fresh is a balanced synergistic mixture that combines the properties of Menthyl nicotinate with the mild refreshing effect of Menthyl lactate.
Nicomenthyl Cool is a balanced synergistic mixture that combines the properties of Menthyl nicotinate with the soothing and cooling effects of natural Menthol.
Mechanism of Action
Once absorbed through the horny layer of the skin, Nicomenthyl® is hydrolized by the enzyme esterase and split into its original components: Niacin and Menthol. Menthol is responsible of the cooling sensory effect, while Niacin generates a kind of warming sensation and furthermore triggers the formation of prostaglandins which cause a mild vasodilation and thus a beneficial enhancement of skin microcirculation.
The main benefits of such enhanced blood flow are: increased transport of Oxygen, Nutrients and Glucose as well as the removal of cellular waste products. All these simultaneous biochemical effects can be perceived as a kind of pleasant “fresh tingling” sensorial effect, usually starting a few minutes (3 to 5) after application, and lasting up to one hour or more.
Patent and Certifications
Multichem R&D is proprietary of several patents regarding Menthyl nicotinate.
MENTHYL NICOTINATE SYNTHESIS PROCESS:
US 10,654,806 B2; Europe EP 3 464 241 B1; Italy 102016000058282; Japan 6648311; Korea 10-2159227; Russia 2018146596; China 201780013935.5; India 201817040202.
NICOMENTHYL APPLICATION PATENTS:
COMPOSITIONS AND METHOD FOR THE STIMULATION OF THE FEMALE AND MALE SEXUAL RESPONSE: US 9,144,572 B2 & EP 2881107B1.